Course Lecturer Name(s): Bawo Teddy Ikolo
Course Director Name: Bawo Teddy Ikolo
Course Lecturer(s) Contact Information: tikolo@sgu.edu
Course Director Contact Information: tikolo@sgu.edu
Course Lecturer(s) Office Hours: Tues, Wed & Thurs 2 – 4 pm. Mondays 10 – 12pm
Course Director Office Hours: Tues, Wed & Thurs 2 – 4 pm. Mondays 10 – 12pm
Course Lecturer(s) Office Location: Caribbean House, 2nd floor
Course Director Office Location: Caribbean House, 2nd floor
Course Support: Akima Ventour, Email: aventou2@sgu.edu, Phone: Ext 3435
Course Management tool: To learn to use Sakai, the Course management tool, access the link https://apps.sgu.edu/members.nsf/mycoursesintro.pdf
Course Description:
Chemistry 224 is a continuation of the material covered in Chemistry 222. Both constitute the oneyear organic chemistry required by most professional schools. Lecture topics include but not limited to the structure, reactivity and synthesis of carbonyl compounds (Aldehydes, ketones, carboxylic acids, anhydrides, acyl halides, esters and amides), amines, aromatic compounds, and biologically related molecules (Carbohydrates, amino acids, and proteins). The course will also provide an introduction to spectroscopy used for the characterization of chemical structures in organic chemistry.
Course Objectives:
The objective of this course is to provide students with an understanding of how the various classes of organic compounds are named, how they are synthesized, their physical and chemical properties, as well as how to determine and analyze their chemical structures using spectroscopy.
Technical Skills Outcomes:
N/A
Student Learning Outcomes:
1). Draw the structure, name and explain the reactivity and synthesis of carbonyl compounds, amines, aromatic compounds, and biologically related molecules (Carbohydrates, amino acids, and proteins).
2). Explain how to carry out functional group interconversions, and discuss the mechanisms of the major chemical reactions like addition, elimination , substitution etc.
3). Interpret results from spectroscopic analysis
Program Outcomes Met By This Course:
BIOL – PLO1: Apply the scientific process for conducting laboratory and diagnostic experiments, testing hypothesis, interpreting data and communicating results
BIOL – PLO4: Apply knowledge of the interaction of atoms , molecules and biochemical processes that define organic and inorganic matter.
SAS Grading Scale: Grades will be assigned as follows:
A = 89.5% or better
B+ = 84.5 - 89.4%
B = 79.5 - 84.4%
C+ = 74.5 - 79.4%
C = 69.5 - 74.4%
D= 64.5 - 69.4%
F = 65% or less
Course Materials:
Text:
1). Organic Chemistry by Wade Jr, L.G. 8th Edition.
2). Fundamentals of organic chemistry by John Murray. 11th edition.
Supplementary Readings/Resources: PowerPoint slides will be provided for each topic covered and will be available on Sakai under the resources folder. Some directed learning activity (DLA) may be given from time to time.
Course Grading Requirement:
The assessments will include Exam 1, Exam 2 (Mid-term exam), Exam 3, and Exam 4 (Final exam). Exams 1 and 3 are valued at 15% each, Mid-term exam 30% and final exam 35%. There will also be two online quizzes valued at 2.5% each. Students need a minimum of a C grade to pass this course.
Course Requirements:
This course will be delivered in person on campus at the scheduled times and venues and streamed live to students. There will also be some directed learning activities (DLA), which students must undertake before attending the preceding lecture.
Students are required to have 70% attendance.
Course Schedule:
|
Lecture |
Week |
Date |
Topics |
|
01 |
1 |
Jan. 17 |
Introduction |
|
02 |
|
Jan. 19 |
Aromatic compounds: Structure of Benzene, stability, aromaticity and Nomenclature of Aromatic compounds |
|
03 |
|
Jan. 21 |
Electrophillic aromatic substitution reactions: General mechanisms. Halogenation, Nitration, Sulfonation and Desulfonation etc |
|
04 |
2 |
Jan. 24 |
The Friedel – Crafts Alkylation and Acylation reactions, and Clemmensen reduction |
|
05 |
|
Jan. 26 |
The effects of substituent in Electrophillic Aromatic substitution & Nucleophillic Aromatic Substitution (Addition -Elimination) |
|
06 |
|
Jan. 28 |
Phenols: Physical properties, reactions and identification |
|
07 |
3 |
Jan. 31 |
Alcohols: Nomenclature, classification, physical properties of alcohols and reasons for exhibiting these properties. |
|
08 |
|
Feb.02 |
Synthesis of alcohols from reduction of Carbonyl compounds and Grignard reaction with carbonyl compounds (Aldehydes, Ketones, Carboxylic acids and esters). |
|
|
|
Feb.04 |
Review |
|
|
4 |
Feb.07 |
Public Holiday |
|
|
|
Feb.09 |
EXAM 1 |
|
9 |
|
Feb.11 |
Reactions of alcohols: Dehydration, Oxidation, Reduction, Esteri |
|
10 |
5 |
Feb.14 |
Aldehydes and Ketones: Structure, reactivity of the carbonyl group. |
|
11 |
|
Feb.16 |
Nomenclature (Naming aldehydes and ketones) |
|
12 |
|
Feb.18 |
Synthesis of aldehydes and ketones: From alkenes, alcohols, nitriles, acid chlorides and esters |
|
13 |
6 |
Feb.21 |
Reactions of aldehydes and ketones/Qualitative tests. Oxidation of aldehydes. Nucleophilic addition reactions of the following: Hydride and Grignard reagents (Alcohol formation), and amines (Imine formation) |
|
14 |
|
Feb.23 |
Carboxylic acids & derivatives: Carboxyl group, acidity of carboxylic acids and effects of substituents, common names versus IUPAC names |
|
15 |
|
Feb. 25 |
Synthesis of carboxylic acids |
|
16 |
7 |
Feb. 28 |
Carboxylic acids & their reactions: General mechanism for nucleophilic acyl substitution. Conversion of carboxylic acids to acid chlorides, esters, amides and alcohols. |
|
17 |
|
Mar. 02 |
Spectroscopy & structure determination: Electromagnetic spectrum basics & types of spectroscopy |
|
|
|
Mar. 04 |
Review |
|
|
8 |
Mar.07- 11 |
Midterm Exam Week |
|
18 |
9 |
Mar.14 |
Infrared spectroscopy of organic molecules & interpreting Infrared spectra |
|
19 |
|
Mar.16 |
Mass spectrometry: Theory, the mass spectrometer, radical ion formation and electron impact ionization |
|
20 |
|
Mar.18 |
. Mass spectrum and interpretations |
|
21 |
10 |
Mar.21 |
Nuclear Magnetic Resonance Spectroscopy: Theory, NMR spectrometer, chemical shift, number of signal and splitting |
|
22 |
|
Mar.23 |
Interpreting 1HMR and 13C spectra |
|
23 |
|
Mar.25 |
Ultraviolet Absorption Spectroscopy: Theory, the UV spectrometer and its use in calculating the concentrations of solutions |
|
24 |
11 |
Mar.28 |
Electrophoresis – Separation of charged particles |
|
25 |
|
Mar.30 |
Ethers, Epoxides: Structure, bonding in ethers, nomenclature and properties |
|
26 |
|
Apr 01 |
Synthesis of ethers: Williamson ether synthesis |
|
|
12 |
Apr 04 |
Review |
|
|
|
Apr. 06 |
EXAM 3 |
|
27 |
|
Apr. 08 |
Reactions of ethers |
|
28 |
13 |
Apr. 11 |
Amines: Structure, properties, nomenclature & synthesis |
|
29 |
|
Apr. 13 |
Reactions of amines |
|
|
|
Apr. 15 |
Public Holiday (Good Friday) |
|
|
14 |
Apr. 18 |
Public Holiday (Easter Monday) |
|
30 |
|
Apr. 20 |
Carbohydrates: Classification, Stereochemistry, Isomerism & Cyclic formation |
|
31 |
|
Apr. 22 |
. Disaccharides and Polysaccharides |
|
32 |
15 |
Apr. 25 |
Proteins: Structure and stereochemistry of the alpha-amino acids. Grouping of amino acids |
|
33 |
14 |
Apr. 27 |
Acid – base properties of amino acids. Levels of protein structure |
|
34 |
|
Apr. 29 |
Lipids: Classification of lipids, triglycerides and phospholipids |
|
|
|
May 01 |
Public Holiday (May day) |
|
|
15 |
May 02 - 06 |
Final Exam Week |
School of Arts and Sciences Master Syllabi — Info for All Sections
Academic Integrity
The St. George’s University Student Manual (2019/2020) states as follows:
“Plagiarism is regarded as a cardinal offense in academia because it constitutes theft of the work of someone else, which is then purported as the original work of the plagiarist. Plagiarism draws into disrepute the credibility of the Institution, its faculty, and students; therefore, it is not tolerated” (p. 48).
Plagiarism also includes the unintentional copying or false accreditation of work, so double check your assignments BEFORE you hand them in.
Be sure to do good, honest work, credit your sources and reference accordingly and adhere to the University’s Honor Code. Plagiarism and cheating will be dealt with very seriously following the university’s policies on Plagiarism as outlined in the Student Manual.
Your work may be subject to submission to plagiarism detection software, submission to this system means that your work automatically becomes part of that database and can be compared with the work of your classmates.
The St. George’s University Student Manual (2019/2020) states as follows:
“Students are expected to attend all classes and or clinical rotations for which they have registered. Although attendance may not be recorded at every academic activity, attendance may be taken randomly. Students’ absence may adversely affect their academic status as specified in the grading policy. If absence from individual classes, examinations, and activities, or from the University itself is anticipated, or occurs spontaneously due to illness or other extenuating circumstances, proper notification procedures must be followed. A particular course may define additional policies regarding specific attendance or participation” (p. 9).
The St. George’s University Student Manual (2019/2020) states as follows:
“All matriculated students are expected to attend all assigned academic activities for each course currently registered. Medical excuses will be based on self-reporting by students. Students who feel they are too sick to take an examination or other required activity on a specific day must submit the online SAS medical excuse, which is available on Carenage. Students are only allowed two such excuses a year. Upon consultation with the Director of University Health Service, the third excuse will result in a mandatory medical leave of absence. The policies regarding make-up examinations are at the option of the Course Director” (p.46).
For additional specific examination policies and procedures, refer to the St. George’s University Student Manual (2019/2020), pages 31 through 37.
The St. George’s University Student Manual (2019/2020) states as follows:
“A student with a disability or disabling condition that affects one or more major life activities, who would like to request an accommodation, must submit a completed application form and supporting documentation to the Student Accessibility and Accommodation Services (SAAS) located in the Dean of Students Office. It is highly recommended that students applying for accommodations do so at least one month before classes begin to allow for a more efficient and timely consideration of the request. If a fully completed application is not submitted in a timely fashion, an eligibility determination may not be made, and accommodations, where applicable, may not be granted prior to the commencement of classes and/or examinations” (p. 8).
It is the responsibility of the student to read and understand the policies, laws, rules and procedures that while they could affect your grade for a course, have not been specifically outlined in the course syllabus. These are contained in the St. George’s University Student Manual.