Biochemistry for Life Sciences

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Course

CHEM 300

Catalog

School of Arts and Sciences

General Course Information

Course Lecturer Name(s): Bawo Teddy Ikolo

Course Director Name: Bawo Teddy Ikolo

Course Lecturer(s) Contact Information: tikolo@sgu.edu

Course Director Contact Information: tikolo@sgu.edu

Course Lecturer(s) Office Hours: Tues, Wed, &Thurs 2- 4pm. Mondays 10 – 12pm

Course Director Office Hours: Tues, Wed & Thurs 2- 4pm. Mon 10am – 12pm

Course Lecturer(s) Office Location: Caribbean House, 2nd floor

Course Director Office Location: Caribbean House, 2nd floor

Course Support: Anna Neckles-Thomas, Email: anecklesthomas@sgu.edu, Phone: Ext. 3435

Course Management tool: To learn to use Sakai, the Course management tool, access the link https://apps.sgu.edu/members.nsf/mycoursesintro.pdf

Course Curriculum Information

Course Description:

This is a one semester course that will introduce students to the Chemistry of living systems at cellular and molecular levels. It will provide an overview of the cell structure, organization, and function. The course will also outline the roles of macromolecules, including carbohydrates, proteins, lipids, and nucleic acids in living systems. Cellular communication and energy production within the cell will also be examined. Biochemical aspects will be integrated with discussions on human health and disease.

Course Objectives:

To critically examine the cell as a unit of life and describe it’s general structure, Organization and function, including its organelles.

To provide a basic description of how cells communicate, transport materials and obtain their energy from biomolecules.

To integrate biochemical pathways as they relate to human health and disease conditions.

Technical Skills Outcomes:

N/A

Student Learning Outcomes:

1). Describe the cell structure, organization and function.

2). Explain how cells communicate and how they generate energy.

3). Outline the roles of macromolecules in living systems and compare both in health and in disease conditions

Program Outcomes Met By This Course:

BIOL – PLO1: Apply the scientific process for conducting laboratory and diagnostic experiments, testing hypothesis, interpreting data and communicating results

BIOL – PLO2: Apply knowledge of the basic structures and fundamental processes of life at the molecular, cellular and organismal levels.

BIOL – PLO3: Apply knowledge of the structure and function of the human body to health issues.

SAS Grading Scale: Grades will be assigned as follows:

A = 89.5% or better

B+ = 84.5 - 89.4%

B = 79.5 - 84.4% \C+ = 74.5 - 79.4%

C = 69.5 - 74.4%

D = 64.5 - 69.4%

F = 65% or less

Course Materials:

Text:

Emine E. Abali, Susan D. Cline, David S. Franklin and Susan M. Viselli (2022). Lippincott’s Illustrated Reviews: Biochemistry. Eight Edition. Lippincott Williams and Wilkins, Baltimore MD, U.S.A.

Chander Nalini and Viselli Susan (2010). Lippincott’s Illustrated Reviews: Cell and Molecular Biology. Series Edition. Lippincott Williams and Wilkins, Baltimore MD, U.S.A.

Horton, H.R., Moran, L.A., Scrimgeour, K.G., Perry, M.D., and Rawn, J.D. (2006). Principles of Biochemistry. Fourth Edition. Pearson Educational Inc., Upper Saddle River, New Jersey, U.S.

Supplementary Readings/Resources: PowerPoint slides will be provided for each topic covered and will be available on Sakai under the resources folder.

Course Grading Requirement:

Four Exams will be held during normal class time. Exam I, II, III and IV. Exam I and III will be valued at 15% each. Exam II (Mid-term examination) will be valued at 25% of your final grade, while Exam IV (Final exam) will also be valued at 30% of your final grade and will test mostly course materials that follow the mid-term exam. Knowledge of material covered in the first part of the course will be an asset for the final exam. There will be five integrated sessions. The best four integrated sessions during the term will be valued at a total of 10% of the final grade. There will also be two online quizzes valued at 2.5% each. Students need a minimum grade of C to pass this course. All exams will be delivered through an on-line platform -Examsoft.

Course Requirements:

This course will be delivered in person on campus at the scheduled times and venues and streamed live to students. There will also be some directed student activities (DLA) which students must undertake before attending the preceding lecture. Students are expected to attend 70% of the classes

Course Schedule:

Biochemistry for Life sciences (CHEM 300) Lecture and Lab schedule Spring 2022

Lecture	Date	Week	Topic				DLA	Textbook	Professor
01	Jan. 18	1 2 3	Introduction to Biochemistry					Prin. Of BCH CHP 1	Ikolo, B
02	Jan. 20		Molecules and chemical reactions of life						Ikolo, B
03	Jan. 21		Cell structure and function				1		Ikolo, B

04	Jan. 25		Protein’s structure and function I
05	Jan. 27		Protein structure and function II					LIRB CHP 1-5	Ikolo, F
06	Jan. 28		Enzyme’s structure and function					LIRB CHP 1-5	Ikolo, F

07	Feb. 01		Carbohydrate’s structure & function I				2
08	Feb. 03		Carbohydrate’s structure & function II					Prin. Of BCH CHP 8	K. James
	Feb. 04			*Integrated:*	*Protein misfolding diseases*

	Feb.07		Public Holiday
	Feb. 08 - 11	4	Exam 1 Week

09	Feb. 15	5	Introduction to lipids					Prin. Of BCH CHP 9	Ikolo, B
10	Feb. 17		Lipids & Biological membranes						Ikolo, B
11	Feb. 18		Membrane transport					LIRC&M CHP 13-19	Ikolo, B

12	Feb. 22	6	Cell-cell communication					LIRC&M CHP 17-19	Ikolo, B
13	Feb. 24		Introduction to metabolism I					LIRB CHP 8	Ikolo, B.
	Feb. 25			*Integrated:*	*Lactose intolerance*

14	Mar. 01	7	Introduction to metabolism II				3	LIRB CHP 8	Ikolo, B.
15	Mar. 03		Energy generation in cells						Ikolo, B.
	Mar. 04			Review
	Mar. 07 - 11	8	Exam II (Mid-term Exam ) Week

16	Mar. 15	9	Gluconeogenesis					LIRB 8 - 10	Ikolo, F
17	Mar. 17		Glycogen metabolism						Ikolo, F
18	Mar. 18		Hexose monophosphate pathway						Ikolo, F

19	Mar. 22	10	Bioenergetics
20	Mar. 24		Photosynthesis				4	Prin. of BCH CHP 15	James
	Mar. 25			*Integrated:*	*Diabetes*

21	Mar. 29	11	General Lipid metabolism
22	Mar. 31		Nitrogen metabolism - Amino acid catabolism & Urea formation					LIRB CHP 19-20	Ikolo, B
	Apr. 01			Review

	Apr. 04 - 08	12	Exam III Week

23	Apr. 12	13 14	Nucleotide metabolism						Ikolo, F
24	Apr. 14		DNA structure and function				5	Genomes 3	Maj
	Apr. 15		Public Holiday (Good Friday)

	Apr 18		Public Holiday (Easter Monday)
25	Apr. 19		RNA structure and function					Genomes 3	Maj
26	Apr. 21		Protein synthesis					Genomes 3	Ikolo, F.
	Apr. 22			Integrated:		*Hypercholesterolaemia*		Genomes 3	Ikolo, F
27	Apr. 26	15	Gene regulation						Ikolo, F
28	Apr. 28		Molecular medicine - Forensics						Ikolo, F
29	Apr. 29			*Integrated:*		*Genetic disorders - sickle cell* Biotechnology
29	Apr. 29			*disorders/*		*Genetic disorders - sickle cell* Biotechnology
	May 02 - 06	16	Exam IV (Final exam) Week				6

School of Arts and Sciences Master Syllabi — Info for All Sections

Plagiarism Policy

Academic Integrity

The St. George’s University Student Manual (2019/2020) states as follows:

“Plagiarism is regarded as a cardinal offense in academia because it constitutes theft of the work of someone else, which is then purported as the original work of the plagiarist. Plagiarism draws into disrepute the credibility of the Institution, its faculty, and students; therefore, it is not tolerated” (p. 48).

Plagiarism also includes the unintentional copying or false accreditation of work, so double check your assignments BEFORE you hand them in.

Be sure to do good, honest work, credit your sources and reference accordingly and adhere to the University’s Honor Code. Plagiarism and cheating will be dealt with very seriously following the university’s policies on Plagiarism as outlined in the Student Manual.

Your work may be subject to submission to plagiarism detection software, submission to this system means that your work automatically becomes part of that database and can be compared with the work of your classmates.

Attendance Requirement

The St. George’s University Student Manual (2019/2020) states as follows:

“Students are expected to attend all classes and or clinical rotations for which they have registered. Although attendance may not be recorded at every academic activity, attendance may be taken randomly. Students’ absence may adversely affect their academic status as specified in the grading policy. If absence from individual classes, examinations, and activities, or from the University itself is anticipated, or occurs spontaneously due to illness or other extenuating circumstances, proper notification procedures must be followed. A particular course may define additional policies regarding specific attendance or participation” (p. 9).

Examination Attendance

The St. George’s University Student Manual (2019/2020) states as follows:

“All matriculated students are expected to attend all assigned academic activities for each course currently registered. Medical excuses will be based on self-reporting by students. Students who feel they are too sick to take an examination or other required activity on a specific day must submit the online SAS medical excuse, which is available on Carenage. Students are only allowed two such excuses a year. Upon consultation with the Director of University Health Service, the third excuse will result in a mandatory medical leave of absence. The policies regarding make-up examinations are at the option of the Course Director” (p.46).

For additional specific examination policies and procedures, refer to the St. George’s University Student Manual (2019/2020), pages 31 through 37.

Student Accessibility and Accommodation Services Policy

The St. George’s University Student Manual (2019/2020) states as follows:

“A student with a disability or disabling condition that affects one or more major life activities, who would like to request an accommodation, must submit a completed application form and supporting documentation to the Student Accessibility and Accommodation Services (SAAS) located in the Dean of Students Office. It is highly recommended that students applying for accommodations do so at least one month before classes begin to allow for a more efficient and timely consideration of the request. If a fully completed application is not submitted in a timely fashion, an eligibility determination may not be made, and accommodations, where applicable, may not be granted prior to the commencement of classes and/or examinations” (p. 8).

Disclaimer

It is the responsibility of the student to read and understand the policies, laws, rules and procedures that while they could affect your grade for a course, have not been specifically outlined in the course syllabus. These are contained in the St. George’s University Student Manual.